Peptide Shampoo

Blueprint

Peptide Shampoo - Image 1

Peptide Shampoo by Blueprint is a specialized hair care product formulated to address scalp health and hair strength through advanced peptide technology. Unlike conventional shampoos, this product acts as both a cleanser and a scalp treatment, making it ideal for those seeking to improve the appearance of thinning or weakened hair. Its gentle, sulfate-free formula is suitable for daily use and safe for color-treated hair, ensuring it fits seamlessly into most hair care routines.

The shampoo’s core innovation lies in its blend of eight encapsulated peptides, including sh-Oligopeptide-1, sh-Polypeptide-7, and sh-Polypeptide-71, which are designed to support the scalp’s natural barrier and encourage healthier hair growth. These peptides are complemented by VEGF (Vascular Endothelial Growth Factor) to help nourish the scalp, while arginine and menthol provide a refreshing sensation and further support scalp circulation. Additional actives such as caffeine, niacinamide, copper tripeptide-1, panthenol, and silk amino acids work synergistically to strengthen hair fibers, improve resilience, and enhance overall scalp condition.

The formula is free from sulfates, silicones, synthetic fragrances, and harsh surfactants, reducing the risk of irritation and buildup. Instead, it uses gentle cleansing agents like sodium cocoyl apple amino acids and coco-glucoside to effectively remove impurities without stripping natural oils. This makes it suitable for sensitive scalps and those who wash their hair frequently. The inclusion of natural extracts like Mentha Arvensis Herb Oil and curcumin further soothes and revitalizes the scalp.

Peptide Shampoo by Blueprint is ideal for individuals experiencing hair thinning, scalp sensitivity, or anyone looking to maintain optimal scalp health and hair density. Its third-party verification ensures quality and safety, making it a trustworthy choice for daily hair care. For best results, apply to wet hair, massage into the scalp, and rinse thoroughly, allowing the active ingredients to work at the root level for stronger, fuller-looking hair over time.

Ingredients

Active Ingredients

Caffeine
StimulantModerate Risk

Caffeine is a natural stimulant commonly found in coffee, tea, and energy drinks, known for enhancing alertness, cognitive function, and physical performance. It works by blocking adenosine receptors in the brain, leading to increased neuronal activity and the release of stimulating neurotransmitters. While moderate consumption offers benefits such as improved mood, reduced risk of certain neurodegenerative diseases, and enhanced metabolism, excessive intake can cause side effects like insomnia and increased heart rate, especially in sensitive individuals.

Mentha Arvensis Herb Oil
Essential Oil / Botanical ExtractModerate Risk

Mentha Arvensis Herb Oil, also known as wild mint oil, is a potent essential oil valued for its cooling, pain-relieving, and respiratory benefits, thanks to its high menthol content. It is commonly used in topical balms, aromatherapy, and wellness products to soothe muscle aches, clear nasal passages, and invigorate the mind. While effective, it should be used with caution due to risks of skin irritation, allergic reactions, and contraindications for certain populations.

3-O-Ethyl Ascorbic Acid
Antioxidant, Skin BrightenerLow Risk

3-O-Ethyl Ascorbic Acid is a stable, next-generation vitamin C derivative prized for its superior skin penetration and antioxidant power. It brightens skin, fades hyperpigmentation, and supports collagen production with less irritation than traditional ascorbic acid. Well-tolerated for most users, it offers enhanced efficacy in both skincare and supplements, though mild irritation is possible at high concentrations or when combined with other actives.

Adenosine
Cellular energy regulator and neurotransmitterLow Risk

Adenosine is a naturally occurring molecule essential for cellular energy transfer and signaling, playing a key role in sleep regulation, cardiovascular function, and immune response. It acts by binding to adenosine receptors, promoting relaxation, vasodilation, and anti-inflammatory effects. Supporting natural adenosine pathways through lifestyle choices can enhance health, while caution is advised with substances that alter its signaling, especially in individuals with cardiovascular conditions or those on specific medications.

Arginine
Amino AcidLow Risk

Arginine is a naturally occurring amino acid essential for nitric oxide production, which supports cardiovascular health by improving blood flow and reducing blood pressure. It also aids immune function, wound healing, and hormone regulation, making it beneficial for exercise performance and recovery. While generally safe, arginine may cause mild gastrointestinal side effects and interact with certain medications, so medical consultation is advised before use.

Copper Tripeptide-1
Skin and Tissue Repair PeptideLow Risk

Copper Tripeptide-1 is a small peptide complexed with copper that supports skin health, tissue repair, and inflammation reduction. It stimulates collagen and elastin production, promoting skin elasticity and wound healing, while also providing antioxidant protection. Commonly used in topical and oral formulations, it offers benefits for skin rejuvenation, hair growth, and joint recovery, with generally low risk when used appropriately.

Curcumin
Antioxidant, Anti-inflammatoryLow Risk

Curcumin is the active compound in turmeric known for its powerful antioxidant and anti-inflammatory properties. It supports joint health, cognitive function, metabolic health, and may aid in cancer prevention. While generally safe, high doses can cause gastrointestinal issues and it may interact with blood-thinning medications, so medical advice is recommended for certain individuals.

Menthol
Cooling agent, Analgesic, Respiratory aidLow Risk

Menthol is a naturally derived compound from mint plants known for its cooling sensation and analgesic properties. It activates TRPM8 receptors to provide pain relief and a cooling effect, making it useful in topical pain relief and respiratory comfort products. While generally safe, menthol can cause skin irritation or allergic reactions and should be used cautiously in individuals with respiratory conditions or when combined with certain medications.

Niacinamide
Vitamin B3 derivative, NutrientLow Risk

Niacinamide, a form of vitamin B3, is essential for cellular energy metabolism, DNA repair, and inflammation modulation. It supports skin health by improving barrier function and reducing acne, while also enhancing metabolic and neurological health. Generally well-tolerated, it offers broad benefits with minimal side effects, making it a versatile nutrient for overall wellness.

Panthenol
Moisturizer, Anti-inflammatory, Hair conditioning agentLow Risk

Panthenol, or provitamin B5, is a moisturizing and healing ingredient widely used in skincare and haircare products. It acts as a humectant, drawing moisture into skin and hair, improving hydration, elasticity, and barrier function, while also providing anti-inflammatory benefits. Generally safe, it may cause mild irritation in sensitive users and supports skin repair and hair strength effectively.

sh-Oligopeptide-1
Skin Conditioning Agent / Growth FactorLow Risk

sh-Oligopeptide-1 (Epidermal Growth Factor, EGF) is a biotechnologically derived peptide that stimulates skin cell renewal, collagen production, and tissue repair, making it a powerful anti-aging and recovery ingredient. It is widely used to improve skin texture, elasticity, and healing, especially after cosmetic procedures. Generally well-tolerated, it may cause mild irritation in sensitive individuals and should be used with caution alongside other potent actives or in special populations.

sh-Oligopeptide-4
Peptide / Skin Conditioning AgentLow Risk

sh-Oligopeptide-4 is a synthetic bioactive peptide that mimics natural growth factors, promoting skin repair, collagen production, and rejuvenation. Widely used in advanced skincare, it helps reduce fine lines, improve elasticity, and accelerate wound healing. Generally well-tolerated, it may cause mild irritation in sensitive individuals or when combined with other potent actives.

sh-Polypeptide-1
Growth Factor / Skin Conditioning AgentLow Risk

sh-Polypeptide-1 (synthetic human oligopeptide-1 or EGF) is a lab-engineered peptide that mimics the body’s natural epidermal growth factor, promoting cell growth, repair, and regeneration. Widely used in advanced skincare, it helps enhance skin resilience, accelerate recovery, and support tissue health, with a strong safety profile for most users. Mild irritation or sensitivity may occur in some individuals, so gradual introduction and patch testing are recommended.

sh-Polypeptide-11
Bioengineered Peptide / Growth Factor MimeticLow Risk

sh-Polypeptide-11 is a bioengineered peptide that mimics natural growth factors, supporting skin repair, renewal, and collagen production. It is valued for its ability to improve skin texture, firmness, and radiance, making it a popular choice in anti-aging and regenerative skincare. Generally well-tolerated, it should be introduced gradually, especially for sensitive skin, to minimize the risk of mild irritation.

sh-Polypeptide-7
Bioengineered Peptide / Growth Factor MimeticLow Risk

sh-Polypeptide-7 is a bioengineered peptide that mimics human growth factors, supporting cellular communication and tissue repair. Commonly used in advanced skincare, it helps improve skin texture, hydration, and resilience by stimulating collagen and elastin production. Generally well-tolerated, it offers gradual, science-backed benefits for skin renewal, though mild irritation is possible for sensitive users.

sh-Polypeptide-71
Bioengineered Peptide / Skin Conditioning AgentLow Risk

sh-Polypeptide-71 is a bioengineered peptide that mimics natural growth factors, supporting skin repair, collagen production, and cellular resilience. It is primarily used in topical skincare to improve texture, elasticity, and visible signs of aging. Generally well-tolerated, it may cause mild irritation in sensitive individuals, so patch testing and gradual introduction are recommended.

sh-Polypeptide-9
Peptide / Growth FactorLow Risk

sh-Polypeptide-9 is a synthetic peptide that mimics human growth factors, widely used in advanced skincare for its regenerative and anti-aging benefits. It stimulates collagen production, supports tissue repair, and enhances skin resilience, making it popular for improving texture and reducing fine lines. Generally well-tolerated, it may cause mild irritation in sensitive individuals, so patch testing is recommended.

Silk Amino Acids
Amino Acid SupplementLow Risk

Silk Amino Acids are rapidly absorbed amino acid chains derived from silkworm cocoons, prized for supporting muscle recovery, skin health, and overall vitality. Their unique structure allows for quick utilization by the body, making them popular among athletes and those seeking enhanced skin resilience. Generally well-tolerated, they may cause mild digestive issues or allergic reactions in sensitive individuals, so consultation with a healthcare provider is recommended for those with underlying health concerns.

Tetrahydrocurcumin
AntioxidantLow Risk

Tetrahydrocurcumin is a highly bioavailable metabolite of curcumin, renowned for its potent antioxidant and anti-inflammatory properties. It supports joint health, metabolic function, and cardiovascular wellness by neutralizing free radicals and modulating inflammation. Generally well-tolerated, it offers enhanced absorption compared to curcumin, but those on certain medications or with gallbladder issues should consult a healthcare provider before use.

Inactive Ingredients

Polysorbate 60
EmulsifierModerate Risk

Polysorbate 60 is a synthetic emulsifier used to stabilize oil and water mixtures in food, pharmaceuticals, and cosmetics. It plays a role in enhancing nutrient and medication absorption by influencing fat processing in the digestive system. While generally safe at typical exposure levels, high intake or sensitivity may disrupt gut microbiota and cause inflammation, making cautious use important for individuals with digestive or immune concerns.

Sodium chloride
Electrolyte, NutrientModerate Risk

Sodium chloride, commonly known as table salt, is an essential electrolyte that supports fluid balance, nerve transmission, and muscle function in the body. It plays a critical role in maintaining blood pressure and nutrient absorption but requires balanced intake to avoid health risks such as hypertension and cardiovascular diseases. Personalized sodium consumption and attention to dietary sources are important for optimizing health outcomes.

Aqua
Essential nutrientLow Risk

Aqua, or water, is an essential nutrient vital for maintaining hydration, supporting physiological functions like nutrient transport, temperature regulation, and waste elimination. Proper hydration enhances cognitive function, physical performance, and skin health, while excessive intake can lead to hyponatremia, especially in endurance athletes or individuals with certain medical conditions.

Betaine
Methyl donor, OsmolyteLow Risk

Betaine, also known as trimethylglycine, is a naturally occurring compound that supports methylation processes essential for DNA repair, detoxification, and neurotransmitter synthesis. It helps lower homocysteine levels, promoting cardiovascular health, supports liver function by reducing fat accumulation, and enhances physical performance through improved cellular hydration. Generally well-tolerated, betaine should be used cautiously in certain populations and under medical supervision when combined with specific medications.

Caprylyl/Capryl Glucoside
Surfactant / CleanserLow Risk

Caprylyl/Capryl Glucoside is a plant-derived, non-ionic surfactant used in personal care products for gentle cleansing and solubilization. It effectively removes dirt and oil while preserving the skin barrier, making it ideal for sensitive or compromised skin. Generally well-tolerated, it offers a mild alternative to harsher surfactants, though rare mild irritation may occur in very sensitive users.

Citric Acid
Metabolic compound, Antioxidant, Food additiveLow Risk

Citric acid is a natural organic acid found in citrus fruits that plays a crucial role in cellular energy production through the Krebs cycle and acts as a potent antioxidant. It supports nutrient absorption, kidney health by preventing stone formation, and may aid in weight management and gut health. Generally safe, it should be consumed with caution by those with citrus allergies or certain medical conditions.

Coco-glucoside
SurfactantLow Risk

Coco-glucoside is a natural, gentle surfactant derived from coconut oil and fruit sugars, widely used in personal care products for effective yet mild cleansing. It helps maintain skin and hair moisture without stripping natural oils, making it suitable for sensitive skin and eco-conscious consumers. Its biodegradable nature and mild conditioning properties make it a popular choice in clean beauty formulations focused on sustainability and skin health.

Decyl Glucoside
Mild SurfactantLow Risk

Decyl Glucoside is a gentle, non-ionic surfactant derived from natural sources like corn glucose, widely used in personal care products for its mild cleansing and foaming properties. It is biodegradable and environmentally friendly, making it suitable for sensitive skin, children, and eco-conscious consumers. Its ability to maintain the skin's moisture barrier and enhance ingredient delivery makes it a valuable ingredient in skincare formulations.

Disodium Lauryl Sulfosuccinate
SurfactantLow Risk

Disodium Lauryl Sulfosuccinate (DLS) is a mild surfactant commonly used in personal care products for gentle yet effective cleansing. It reduces surface tension to lift oils and dirt without stripping natural skin oils, making it suitable for sensitive skin and conditions like eczema. DLS supports skin barrier integrity and microbiome balance, with a favorable safety profile compared to harsher detergents, though mild irritation may occur in some users.

Glycerin
Humectant, Energy Metabolism Support, Skin Hydration AgentLow Risk

Glycerin, also known as glycerol, is a naturally occurring polyol compound that acts primarily as a humectant to retain moisture in the skin, promoting hydration and elasticity. It also supports energy metabolism by converting into glucose, providing a quick energy source, and helps regulate fluid balance in the body. Widely used in skincare and athletic supplements, glycerin offers benefits for skin health, endurance, and hydration, though caution is advised for those with diabetes or gastrointestinal sensitivity.

Glyceryl Caprylate
Antimicrobial, EmollientLow Risk

Glyceryl Caprylate is a naturally derived antimicrobial and moisturizing ingredient commonly used in skincare to support skin barrier function and maintain a balanced microbiome. It selectively disrupts harmful microbes while preserving beneficial skin flora, helping to reduce irritation and improve skin texture. Suitable for sensitive skin, it also acts as an emollient to lock in hydration, making it beneficial for managing inflammatory skin conditions and promoting overall skin health.

Glycol Distearate
Emulsifier / OpacifierLow Risk

Glycol Distearate is a waxy compound used as an emulsifier and opacifier in personal care products, providing a pearly sheen and stable texture. It helps evenly distribute active ingredients, supporting skin and hair hydration and barrier function. Generally considered safe and non-irritating, it may rarely cause mild irritation in sensitive users.

Hexylene Glycol
Solvent / HumectantLow Risk

Hexylene Glycol is a versatile solvent and humectant commonly used in skincare and pharmaceutical products to enhance ingredient penetration and retain moisture. It helps improve the effectiveness of active compounds and supports skin hydration, making it valuable for both cosmetic and medicinal formulations. Generally well-tolerated, it may cause mild irritation in sensitive individuals or increase absorption of other actives, so patch testing and mindful use are recommended.

Lauramidopropyl Betaine
Surfactant / Cleansing AgentLow Risk

Lauramidopropyl betaine is a coconut-derived, gentle surfactant commonly used in shampoos and body washes for its mild cleansing properties. It effectively removes dirt and oil without stripping the skin or hair of natural moisture, making it ideal for sensitive or dry skin. While generally well-tolerated, rare cases of mild irritation or allergic reactions may occur, so patch-testing is recommended for those with very sensitive skin.

Lauryl Glucoside
Mild SurfactantLow Risk

Lauryl Glucoside is a gentle, non-ionic surfactant derived from natural sources like coconut and corn glucose, commonly used in personal care products for its effective yet mild cleansing properties. It supports skin health by maintaining hydration and minimizing irritation, making it suitable for sensitive skin types. Additionally, it is biodegradable and environmentally friendly, aligning with clean and sustainable beauty trends.

Lecithin
Phospholipid, Emulsifier, NutrientLow Risk

Lecithin is a naturally occurring phospholipid essential for cell membrane integrity and fat metabolism. It acts as an emulsifier aiding fat digestion and absorption, supports brain and liver health through its choline content, and may help lower cholesterol and reduce inflammation. Generally safe, lecithin should be used cautiously by those with soy allergies or on certain medications.

Limonene
Fragrance allergen, Antioxidant, Anti-inflammatoryLow Risk

Limonene is a naturally occurring terpene found in citrus fruit peels, known for its refreshing scent and health benefits including anti-inflammatory, antioxidant, and mood-enhancing properties. It supports mental well-being by modulating neurotransmitters and aids digestive health, while emerging research suggests potential anti-cancer and metabolic benefits. Generally safe, limonene should be used cautiously by those with citrus allergies or on certain medications.

Pentylene Glycol
Humectant, Solvent, Antimicrobial AgentLow Risk

Pentylene Glycol is a multifunctional ingredient used in skincare for its humectant properties that help retain moisture and improve skin hydration. It also acts as a solvent enhancing the delivery of active compounds and has antimicrobial effects that aid in product preservation. Generally well-tolerated, it may cause mild irritation in sensitive individuals and can increase absorption of topical medications, warranting caution when used with prescription treatments.

Phenoxyethanol
PreservativeLow Risk

Phenoxyethanol is a glycol ether used primarily as a preservative and antimicrobial agent in cosmetics and personal care products. It helps maintain product safety by preventing microbial growth and stabilizing formulations, making it suitable for sensitive skin due to its low toxicity. While generally safe, some individuals may experience sensitivity, and caution is advised for pregnant or breastfeeding users.

Polyquaternium-10
Conditioning polymerLow Risk

Polyquaternium-10 is a synthetic conditioning polymer commonly used in hair conditioners and skin moisturizers to improve texture, enhance moisture retention, and form a protective barrier. It works by electrostatically binding to hair and skin surfaces, reducing friction, locking in moisture, and supporting repair of minor damage. Generally safe with low risk, it may cause mild irritation in sensitive users and can lead to buildup if overused.

Sodium citrate
Buffering agent, Preservative, Metabolic enhancerLow Risk

Sodium citrate is a sodium salt of citric acid used as a preservative and flavoring agent, with notable benefits in metabolic health and exercise performance. It acts as a buffering agent to regulate acidity in the body, enhancing endurance by neutralizing lactic acid buildup during intense exercise. Additionally, it supports energy metabolism through its role in the Krebs cycle and may improve insulin sensitivity and kidney health, making it a versatile supplement for fitness and metabolic support.

Sodium Cocoyl Apple Amino Acids
Surfactant / Cleansing AgentLow Risk

Sodium Cocoyl Apple Amino Acids is a plant-based surfactant derived from apple amino acids and coconut fatty acids, prized for its gentle, skin-friendly cleansing action. It effectively removes dirt and oil without disrupting the skin’s natural barrier, making it ideal for sensitive or reactive skin types. With a low risk of irritation and strong support for skin hydration and barrier function, it’s a standout choice for those seeking mild, eco-conscious skincare solutions.

Tetrasodium Glutamate Diacetate
Chelating agentLow Risk

Tetrasodium Glutamate Diacetate (TGD) is a chelating agent derived from glutamic acid that enhances nutrient absorption and stabilizes essential minerals in the body. It improves bioavailability by binding minerals like calcium, magnesium, and iron, facilitating their efficient uptake and supporting overall health. TGD may also aid in detoxification by binding heavy metals, but users should be cautious of mild gastrointestinal side effects and consult healthcare providers if pregnant, breastfeeding, or on medication.

Trehalose
Carbohydrate, Neuroprotective agent, Metabolic health supportLow Risk

Trehalose is a naturally occurring disaccharide sugar composed of two glucose molecules, known for its ability to stabilize proteins and support cellular health. It offers potential neuroprotective benefits, enhances autophagy for cellular renewal, and may improve metabolic health by enhancing insulin sensitivity. Generally safe, trehalose should be used cautiously by individuals with diabetes or gastrointestinal sensitivities.