Peptide Serum

Blueprint

Peptide Serum - Image 1

Peptide Serum by Blueprint is a cutting-edge topical haircare solution formulated to support the appearance of thicker, healthier hair. Utilizing a sophisticated blend of eight advanced peptides, growth factors, and a range of scientifically backed ingredients, this serum targets the scalp and hair follicles to address common concerns such as thinning, breakage, and lack of resilience. The product is delivered through a nanoliposome system, which enhances the penetration and effectiveness of its active components, ensuring that the scalp and follicles receive optimal nourishment.

Key ingredients include copper tripeptide-1, known for its role in supporting hair growth and scalp health, niacinamide for improving scalp hydration and barrier function, and caffeine to stimulate hair follicles. Additional actives like tetrahydrocurcumin, glutathione, and panthenol provide antioxidant protection and help strengthen hair strands, while growth factors and oligopeptides work synergistically to promote the look of fuller, denser hair. The inclusion of DNA (PDRN) and adenosine further supports cellular repair and scalp vitality.

Peptide Serum is lightweight, non-greasy, and non-comedogenic, making it suitable for daily use without weighing hair down or clogging pores. It is free from synthetic fragrances, sulfates, and parabens, catering to those with sensitive scalps or those seeking a cleaner haircare routine. The serum is also third-party verified, providing additional assurance of its quality and safety.

This product is ideal for individuals experiencing hair thinning, breakage, or those simply looking to enhance the overall health and appearance of their hair. Regular use can help reduce visible breakage, support scalp hydration, and promote stronger, more resilient hair. For best results, apply directly to the scalp as part of your daily haircare regimen, gently massaging it in to maximize absorption and benefits.

Ingredients

Active Ingredients

Caffeine
StimulantModerate Risk

Caffeine is a natural stimulant commonly found in coffee, tea, and energy drinks, known for enhancing alertness, cognitive function, and physical performance. It works by blocking adenosine receptors in the brain, leading to increased neuronal activity and the release of stimulating neurotransmitters. While moderate consumption offers benefits such as improved mood, reduced risk of certain neurodegenerative diseases, and enhanced metabolism, excessive intake can cause side effects like insomnia and increased heart rate, especially in sensitive individuals.

Salicylic Acid
Keratolytic agent, Anti-inflammatoryModerate Risk

Salicylic acid is a naturally derived keratolytic and anti-inflammatory agent widely used in skincare to exfoliate dead skin cells, treat acne, and reduce inflammation. It also has systemic importance through its derivatives like aspirin, which aid in pain relief and cardiovascular health. While effective, it may cause skin irritation topically and carries risks such as gastrointestinal issues when used systemically, necessitating cautious use especially in sensitive individuals.

3-O-Ethyl Ascorbic Acid
Antioxidant, Skin BrightenerLow Risk

3-O-Ethyl Ascorbic Acid is a stable, next-generation vitamin C derivative prized for its superior skin penetration and antioxidant power. It brightens skin, fades hyperpigmentation, and supports collagen production with less irritation than traditional ascorbic acid. Well-tolerated for most users, it offers enhanced efficacy in both skincare and supplements, though mild irritation is possible at high concentrations or when combined with other actives.

Acetyl Cysteine
Antioxidant, Mucolytic, Amino Acid DerivativeLow Risk

Acetyl cysteine (NAC) is a powerful antioxidant and amino acid derivative known for replenishing glutathione, supporting detoxification, and acting as a mucolytic to ease respiratory issues. Widely used for liver support, respiratory health, and emerging mental wellness benefits, NAC is generally well tolerated but may cause mild digestive upset and interact with certain medications. Its versatility and robust clinical backing make it a valuable supplement for cellular defense and recovery, though medical guidance is recommended for those with chronic conditions or on prescription drugs.

Adenosine
Cellular energy regulator and neurotransmitterLow Risk

Adenosine is a naturally occurring molecule essential for cellular energy transfer and signaling, playing a key role in sleep regulation, cardiovascular function, and immune response. It acts by binding to adenosine receptors, promoting relaxation, vasodilation, and anti-inflammatory effects. Supporting natural adenosine pathways through lifestyle choices can enhance health, while caution is advised with substances that alter its signaling, especially in individuals with cardiovascular conditions or those on specific medications.

Arginine
Amino AcidLow Risk

Arginine is a naturally occurring amino acid essential for nitric oxide production, which supports cardiovascular health by improving blood flow and reducing blood pressure. It also aids immune function, wound healing, and hormone regulation, making it beneficial for exercise performance and recovery. While generally safe, arginine may cause mild gastrointestinal side effects and interact with certain medications, so medical consultation is advised before use.

Copper Tripeptide-1
Skin and Tissue Repair PeptideLow Risk

Copper Tripeptide-1 is a small peptide complexed with copper that supports skin health, tissue repair, and inflammation reduction. It stimulates collagen and elastin production, promoting skin elasticity and wound healing, while also providing antioxidant protection. Commonly used in topical and oral formulations, it offers benefits for skin rejuvenation, hair growth, and joint recovery, with generally low risk when used appropriately.

Curcumin
Antioxidant, Anti-inflammatoryLow Risk

Curcumin is the active compound in turmeric known for its powerful antioxidant and anti-inflammatory properties. It supports joint health, cognitive function, metabolic health, and may aid in cancer prevention. While generally safe, high doses can cause gastrointestinal issues and it may interact with blood-thinning medications, so medical advice is recommended for certain individuals.

DNA (PDRN)
Regenerative agent / Skin rejuvenationLow Risk

DNA (PDRN), or Polydeoxyribonucleotide, is a DNA fragment complex often derived from salmon, used in regenerative medicine and skin rejuvenation. It accelerates tissue repair, reduces inflammation, and supports cellular renewal, making it valuable for wound healing and cosmetic improvements. Generally well-tolerated, PDRN may cause mild irritation or rare allergic reactions, especially in those with fish allergies, so professional guidance is recommended.

Glutathione
AntioxidantLow Risk

Glutathione is a powerful, naturally occurring antioxidant crucial for cellular health, detoxification, and immune function. It protects cells from oxidative stress, supports liver detoxification, and helps maintain immune resilience. While generally safe, supplementation with precursors like N-acetylcysteine requires caution due to potential side effects and drug interactions.

Glycine
Amino AcidLow Risk

Glycine is a non-essential amino acid vital for protein synthesis, particularly collagen, supporting skin, joint, and connective tissue health. It functions as an inhibitory neurotransmitter promoting relaxation and sleep quality, and aids in antioxidant production and metabolic health. Generally safe with low risk, glycine supplementation may cause mild digestive issues and should be used cautiously with certain health conditions and medications.

Ketoglutaric Acid
Metabolic Support / Cellular HealthLow Risk

Ketoglutaric acid (alpha-ketoglutarate, AKG) is a key metabolic molecule central to energy production, amino acid metabolism, and cellular signaling. Popular as a supplement for muscle health, recovery, and longevity, AKG supports mitochondrial function and may help preserve lean muscle mass, especially in aging or stressed individuals. Generally well-tolerated, it should be used with caution by those with kidney or liver issues and may cause mild digestive upset at higher doses.

Niacinamide
Vitamin B3 derivative, NutrientLow Risk

Niacinamide, a form of vitamin B3, is essential for cellular energy metabolism, DNA repair, and inflammation modulation. It supports skin health by improving barrier function and reducing acne, while also enhancing metabolic and neurological health. Generally well-tolerated, it offers broad benefits with minimal side effects, making it a versatile nutrient for overall wellness.

Nicotinamide mononucleotide
Cellular metabolism and anti-aging compoundLow Risk

Nicotinamide mononucleotide (NMN) is a naturally occurring molecule that serves as a direct precursor to NAD+, essential for cellular energy metabolism, DNA repair, and aging processes. Supplementation with NMN supports healthy aging, metabolic function, and cellular resilience by replenishing NAD+ levels, enhancing mitochondrial function, and activating longevity-related proteins. While generally safe, NMN may cause mild side effects and interact with certain medications, so consultation with a healthcare provider is recommended.

Panthenol
Moisturizer, Anti-inflammatory, Hair conditioning agentLow Risk

Panthenol, or provitamin B5, is a moisturizing and healing ingredient widely used in skincare and haircare products. It acts as a humectant, drawing moisture into skin and hair, improving hydration, elasticity, and barrier function, while also providing anti-inflammatory benefits. Generally safe, it may cause mild irritation in sensitive users and supports skin repair and hair strength effectively.

sh-Oligopeptide-1
Skin Conditioning Agent / Growth FactorLow Risk

sh-Oligopeptide-1 (Epidermal Growth Factor, EGF) is a biotechnologically derived peptide that stimulates skin cell renewal, collagen production, and tissue repair, making it a powerful anti-aging and recovery ingredient. It is widely used to improve skin texture, elasticity, and healing, especially after cosmetic procedures. Generally well-tolerated, it may cause mild irritation in sensitive individuals and should be used with caution alongside other potent actives or in special populations.

sh-Oligopeptide-4
Peptide / Skin Conditioning AgentLow Risk

sh-Oligopeptide-4 is a synthetic bioactive peptide that mimics natural growth factors, promoting skin repair, collagen production, and rejuvenation. Widely used in advanced skincare, it helps reduce fine lines, improve elasticity, and accelerate wound healing. Generally well-tolerated, it may cause mild irritation in sensitive individuals or when combined with other potent actives.

sh-Polypeptide-4
Synthetic Growth Factor / Bioengineered PeptideLow Risk

sh-Polypeptide-4 is a bioengineered peptide that mimics natural growth factors, supporting skin repair, collagen production, and cellular rejuvenation. Commonly used in advanced skincare, it helps improve skin texture, firmness, and resilience, with emerging research suggesting benefits for wound healing and tissue regeneration. Generally well-tolerated, it may cause mild irritation in sensitive individuals and should be used with caution by those with certain skin conditions.

sh-Polypeptide-59
Bioengineered Peptide / Growth Factor MimeticLow Risk

sh-Polypeptide-59 is a bioengineered peptide designed to mimic natural growth factors, supporting cellular repair and skin rejuvenation. Leveraging recombinant DNA technology, it activates the body’s intrinsic healing mechanisms, making it valuable in advanced skincare and regenerative health. Generally well-tolerated, it may cause mild irritation in sensitive individuals and should be introduced gradually, especially when combined with other potent actives.

sh-Polypeptide-7
Bioengineered Peptide / Growth Factor MimeticLow Risk

sh-Polypeptide-7 is a bioengineered peptide that mimics human growth factors, supporting cellular communication and tissue repair. Commonly used in advanced skincare, it helps improve skin texture, hydration, and resilience by stimulating collagen and elastin production. Generally well-tolerated, it offers gradual, science-backed benefits for skin renewal, though mild irritation is possible for sensitive users.

sh-Polypeptide-86
Bioengineered Peptide / Skin Conditioning AgentLow Risk

sh-Polypeptide-86 is a synthetic peptide designed to mimic natural growth factors, promoting skin repair, regeneration, and collagen production. It is primarily used in topical skincare for its anti-aging and rejuvenating effects, with emerging research suggesting broader tissue health benefits. Generally well-tolerated, it may cause mild irritation in sensitive individuals and should be used with care alongside other potent actives.

sh-Polypeptide-9
Peptide / Growth FactorLow Risk

sh-Polypeptide-9 is a synthetic peptide that mimics human growth factors, widely used in advanced skincare for its regenerative and anti-aging benefits. It stimulates collagen production, supports tissue repair, and enhances skin resilience, making it popular for improving texture and reducing fine lines. Generally well-tolerated, it may cause mild irritation in sensitive individuals, so patch testing is recommended.

Tetrahydrocurcumin
AntioxidantLow Risk

Tetrahydrocurcumin is a highly bioavailable metabolite of curcumin, renowned for its potent antioxidant and anti-inflammatory properties. It supports joint health, metabolic function, and cardiovascular wellness by neutralizing free radicals and modulating inflammation. Generally well-tolerated, it offers enhanced absorption compared to curcumin, but those on certain medications or with gallbladder issues should consult a healthcare provider before use.

Thioctic Acid
AntioxidantLow Risk

Thioctic acid, also known as alpha-lipoic acid (ALA), is a versatile antioxidant that supports energy metabolism, nerve health, and protection against oxidative stress. Its unique solubility in both water and fat allows it to work throughout the body, recycling other antioxidants and promoting cellular resilience. Generally well-tolerated, it may cause mild side effects or interact with certain medications, especially those affecting blood sugar or thyroid function.

Inactive Ingredients

Polysorbate 60
EmulsifierModerate Risk

Polysorbate 60 is a synthetic emulsifier used to stabilize oil and water mixtures in food, pharmaceuticals, and cosmetics. It plays a role in enhancing nutrient and medication absorption by influencing fat processing in the digestive system. While generally safe at typical exposure levels, high intake or sensitivity may disrupt gut microbiota and cause inflammation, making cautious use important for individuals with digestive or immune concerns.

1,2-hexanediol
Humectant, Antimicrobial agent, PreservativeLow Risk

1,2-Hexanediol is a versatile diol commonly used in skincare for its humectant properties that help retain skin moisture and its antimicrobial effects that protect against bacteria and fungi. It enhances skin hydration, improves the efficacy of other active ingredients, and may support metabolic health through gut microbiota modulation. Generally safe with low toxicity, it should be used with caution by those with sensitive skin to avoid irritation.

Aqua
Essential nutrientLow Risk

Aqua, or water, is an essential nutrient vital for maintaining hydration, supporting physiological functions like nutrient transport, temperature regulation, and waste elimination. Proper hydration enhances cognitive function, physical performance, and skin health, while excessive intake can lead to hyponatremia, especially in endurance athletes or individuals with certain medical conditions.

Citric Acid
Metabolic compound, Antioxidant, Food additiveLow Risk

Citric acid is a natural organic acid found in citrus fruits that plays a crucial role in cellular energy production through the Krebs cycle and acts as a potent antioxidant. It supports nutrient absorption, kidney health by preventing stone formation, and may aid in weight management and gut health. Generally safe, it should be consumed with caution by those with citrus allergies or certain medical conditions.

Glycerin
Humectant, Energy Metabolism Support, Skin Hydration AgentLow Risk

Glycerin, also known as glycerol, is a naturally occurring polyol compound that acts primarily as a humectant to retain moisture in the skin, promoting hydration and elasticity. It also supports energy metabolism by converting into glucose, providing a quick energy source, and helps regulate fluid balance in the body. Widely used in skincare and athletic supplements, glycerin offers benefits for skin health, endurance, and hydration, though caution is advised for those with diabetes or gastrointestinal sensitivity.

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer
Thickening agent, Stabilizer, EmulsifierLow Risk

Hydroxyethyl Acrylate/Sodium Acryloyldimethyl Taurate Copolymer is a synthetic polymer used primarily as a thickening agent, stabilizer, and emulsifier in skincare and cosmetic products. It enhances product texture, stability, and the delivery of active ingredients while supporting skin hydration by forming a breathable film that reduces water loss. Generally safe for topical use, it has a low risk of irritation and is suitable for sensitive and acne-prone skin types.

Lecithin
Phospholipid, Emulsifier, NutrientLow Risk

Lecithin is a naturally occurring phospholipid essential for cell membrane integrity and fat metabolism. It acts as an emulsifier aiding fat digestion and absorption, supports brain and liver health through its choline content, and may help lower cholesterol and reduce inflammation. Generally safe, lecithin should be used cautiously by those with soy allergies or on certain medications.

p-Anisic Acid
Antioxidant, Antimicrobial, Anti-inflammatoryLow Risk

p-Anisic acid (4-methoxybenzoic acid) is a naturally occurring compound found in anise and fennel, prized for its antioxidant, antimicrobial, and anti-inflammatory properties. It helps neutralize free radicals, supports skin barrier health, and may inhibit the growth of certain bacteria and fungi. Generally well-tolerated, it offers benefits for skin and microbiome health, though those with plant allergies or sensitive skin should use with caution.

Pentylene Glycol
Humectant, Solvent, Antimicrobial AgentLow Risk

Pentylene Glycol is a multifunctional ingredient used in skincare for its humectant properties that help retain moisture and improve skin hydration. It also acts as a solvent enhancing the delivery of active compounds and has antimicrobial effects that aid in product preservation. Generally well-tolerated, it may cause mild irritation in sensitive individuals and can increase absorption of topical medications, warranting caution when used with prescription treatments.

Sodium citrate
Buffering agent, Preservative, Metabolic enhancerLow Risk

Sodium citrate is a sodium salt of citric acid used as a preservative and flavoring agent, with notable benefits in metabolic health and exercise performance. It acts as a buffering agent to regulate acidity in the body, enhancing endurance by neutralizing lactic acid buildup during intense exercise. Additionally, it supports energy metabolism through its role in the Krebs cycle and may improve insulin sensitivity and kidney health, making it a versatile supplement for fitness and metabolic support.